Origin of life
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This is a conversation with Aaron Engelhart, assistant Professor in the University of Minnesota Department of Genetics, Cell Biology, and Development. His research mainly focuses on understanding nucleic acid folding and function. In this conversation we talk about life on Mars, astrobiology, RNA world and tools we are using to find life on Mars.
About the guest
00:00:00 Introduction
00:00:46 What are the major theories in Origin of life?
00:05:22 Major questions Aaron's group is focusing on?
00:08:57 Association with NASA
00:11:11 Life on earth coming from space
00:12:40 Can life forms surviving meteorite explosions?
00:16:02 Similarities between geochemistry of Mars and Earth?
00:20:15 RNA world
00:21:53 RNA as a coding molecule and RNA as a catalytic molecule
00:26:44 Solubility of biomolecules
00:29:47 Problem of the compartmentalization
00:32:55 Link between genetics and compartments
00:36:52 Importance of Watson-Crick paring in DNA
00:39:18 Impact of wet-dry and redox cycles on DNA/RNA
00:42:50 Structures beyond Watson-Crick paring
00:45:26 New imaging tools based on RNA
00:50:22 How the new tools can be used to study Origins of life?
00:54:22 How do we get information from Mars?
00:59:05 Introducing imaging tools to the equipment sent to Mars
01:00:03 Major questions for Aaron
01:03:27 Populating Mars with microbes
01:05:51 Living on Mars
01:06:58 Further reading
01:09:56 Thank you!